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1

Muscarinic acetylcholine receptors: mutant mice provide new insights for drug development

Wess, Jürgen, Eglen, Richard M., Gautam, Dinesh

Journal:

Nature Reviews Drug Discovery

Year:

2007

Language:

english

File:

PDF, 545 KB

english, 2007

2

Role of specific muscarinic receptor subtypes in cholinergic parasympathomimetic responses, in vivo phosphoinositide hydrolysis, and pilocarpine-induced seizure activity

Frank P. Bymaster, Petra A. Carter, Masahisa Yamada, Jesus Gomeza, Jürgen Wess, Susan E. Hamilton, Neil M. Nathanson, David L. McKinzie, Christian C. Felder

Journal:

European Journal of Neuroscience

Year:

2003

Language:

english

File:

PDF, 308 KB

english, 2003

3

Muscarinic receptor subtypes involved in carbachol-induced contraction of mouse uterine smooth muscle

Takio Kitazawa, Ryuichi Hirama, Kozue Masunaga, Tatsuro Nakamura, Koichi Asakawa, Jinshan Cao, Hiroki Teraoka, Toshihiro Unno, Sei-ichi Komori, Masahisa Yamada, Jürgen Wess, Tetsuro Taneike

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

2008

Language:

english

File:

PDF, 334 KB

english, 2008

4

Book Review

Jürgen Wessing

Journal:

Criminal Law Forum

Year:

2011

Language:

english

File:

PDF, 127 KB

english, 2011

5

M USCARINIC A CETYLCHOLINE R ECEPTOR K NOCKOUT M ICE : Novel Phenotypes and Clinical Implications*

Journal:

Annual Review of Pharmacology

Year:

2004

Language:

english

File:

PDF, 281 KB

english, 2004

6

Novel designer receptors to probe GPCR signaling and physiology

Wess, Jürgen, Nakajima, Kenichiro, Jain, Shalini

Journal:

Trends in Pharmacological Sciences

Year:

2013

Language:

english

File:

PDF, 1.07 MB

english, 2013

7

Role of the M 3 Muscarinic Acetylcholine Receptor Subtype in Murine Ophthalmic Arteries After Endothelial Removal

Gericke, Adrian, Steege, Andreas, Manicam, Caroline, Böhmer, Tobias, Wess, Jürgen, Pfeiffer, Norbert

Journal:

Investigative Opthalmology & Visual Science

Year:

2014

Language:

english

File:

PDF, 313 KB

english, 2014

8

BGH v. 27. 1. 2005 – IX ZR 273/02, Angemessenheit der Vergütung eines Strafverteidigers (Wessing)

Wessing, Jürgen

Journal:

Juristische Rundschau

Year:

2006

Language:

german

File:

PDF, 212 KB

german, 2006

9

Wnt/β-catenin signaling is differentially regulated by Gα proteins and contributes to fibrous dysplasia

Jean B. Regard, Natasha Cherman, Daniel Palmer, Sergei A. Kuznetsov, Francesco S. Celi, Jean-Marc Guettier, Min Chen, Nisan Bhattacharyya, Jurgen Wess, Shaun R. Coughlin, Lee S. Weinstein, Michael T.

Journal:

Proceedings of the National Academy of Sciences

Year:

2011

Language:

english

File:

PDF, 1.69 MB

english, 2011

10

Cholinergic Projections to the Substantia Nigra Pars Reticulata Inhibit Dopamine Modulation of Basal Ganglia through the M 4 Muscarinic Receptor

Moehle, Mark S., Pancani, Tristano, Byun, Nellie, Yohn, Samantha E., Wilson, George H., Dickerson, Johnathan W., Remke, Daniel H., Xiang, Zixiu, Niswender, Colleen M., Wess, Jürgen, Jones, Carrie K.,

Journal:

Year:

2017

Language:

english

File:

PDF, 4.98 MB

english, 2017

11

Muscarinic receptors 2 and 5 regulate bitter response of urethral brush cells via negative feedback

Deckmann, Klaus, Rafiq, Amir, Erdmann, Christian, Illig, Christian, Durschnabel, Melanie, Wess, Jürgen, Weidner, Wolfgang, Bschleipfer, Thomas, Kummer, Wolfgang

Journal:

The FASEB Journal

Year:

2018

Language:

english

File:

PDF, 1.49 MB

english, 2018

12

Hepatobiliary transport of hepatic 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors conjugated with bile acids

Prof Dr Ernst Petzinger, Lutz Nickau, Jurgen A. Horz, Siegfried Schulz, Gunther Wess, Alfons Enhsen, Eugen Falk, Karl-Heinz Baringhaus, Heiner Glombik, Axel Hoffmann, Stefan Müllner, Georg Neckermann,

Journal:

Year:

1995

Language:

english

File:

PDF, 1.01 MB

english, 1995

13

Sila-Pharmaka, 33. Synthese und Eigenschaften des selektiven Antimuskarinikums Cyclohexylphenyl-(3-piperidinopropyl)silanol

Reinhold Tacke, Haryanto Linoh, Harald Zilch, Jürgen Wess, Ulrich Moser, Ernst Mutschler, Günter Lambrecht

Journal:

European Journal of Organic Chemistry

Year:

1985

Language:

german

File:

PDF, 365 KB

german, 1985

14

Ein neuer Weg zur Darstellung von Glycofuranosylcyaniden (2,5-Anhydroaldononitrilen). Reduktion von acetylierten 2,5-Anhydro-1-desoxy-1-nitroalditolen mit Phosphortrichlorid

Peter Köll, Jürgen Kopf, Doris Wess, Heinz Brandenburg

Journal:

European Journal of Organic Chemistry

Year:

1988

File:

PDF, 854 KB

1988

15

Role for M5 muscarinic acetylcholine receptors in cocaine addiction

Anders Fink-Jensen, Irina Fedorova, Gitta Wörtwein, David P. D. Woldbye, Thøger Rasmussen, Morgane Thomsen, Tom G. Bolwig, Karen M. Knitowski, David L. McKinzie, Masahisa Yamada, Jürgen Wess, Anthony

Journal:

Journal of Neuroscience Research

Year:

2003

Language:

english

File:

PDF, 90 KB

english, 2003

16

Book Reviews

Journal:

Analytical Biochemistry

Year:

1996

Language:

english

File:

PDF, 32 KB

english, 1996

17

Structural basis of the selectivity of the β2-adrenergic receptor for fluorinated catecholamines

Chaya Pooput, Erica Rosemond, Joel Karpiak, Francesca Deflorian, Santiago Vilar, Stefano Costanzi, Jürgen Wess, Kenneth L. Kirk

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 458 KB

english, 2009

18

Conserved Extracellular Cysteine Pair in the M3 Muscarinic Acetylcholine Receptor Is Essential for Proper Receptor Cell Surface Localization but Not for G Protein Coupling

Fu-Yue Zeng, Andrea Soldner, Torsten Schöneberg, Jürgen Wess

Journal:

Journal of Neurochemistry

Year:

1999

Language:

english

File:

PDF, 247 KB

english, 1999

19

Functional expression of M1, M3 and M5 muscarinic acetylcholine receptors in yeast

Isolde Erlenbach, Evi Kostenis, Clarice Schmidt, Fadi F. Hamdan, Mark H. Pausch, Jürgen Wess

Journal:

Journal of Neurochemistry

Year:

2001

Language:

english

File:

PDF, 773 KB

english, 2001

20

Acyl- und Alkylidenphosphane. XVI. (Dimethylaminomethyliden)- und (Diphenylmethyliden)phosphane

Prof. Dr. Gerd Becker, Dr. Werner Uhl, Stud. Ref. Hans-Jürgen Wessely

Journal:

Zeitschrift für anorganische und allgemeine Chemie

Year:

1981

File:

PDF, 973 KB

1981

21

Heterogeneity of release-inhibiting muscarinic autoreceptors in heart atria and urinary bladder: a study with M2- and M4-receptor-deficient mice

Hongxia Zhou, Angelika Meyer, Klaus Starke, Jesus Gomeza, Jürgen Wess, Anne-Ulrike Trendelenburg

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

2002

Language:

english

File:

PDF, 167 KB

english, 2002

22

Suitability of muscarinic acetylcholine receptor antibodies for immunohistochemistry evaluated on tissue sections of receptor gene-deficient mice

Gitte Jositsch, Tamara Papadakis, Rainer V. Haberberger, Miriam Wolff, Jürgen Wess, Wolfgang Kummer

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

2009

Language:

english

File:

PDF, 256 KB

english, 2009

23

Decreased prepulse inhibition and increased sensitivity to muscarinic, but not dopaminergic drugs in M5muscarinic acetylcholine receptor knockout mice

Morgane Thomsen, Gitta Wörtwein, Anders Fink-Jensen, David P. D. Woldbye, Jürgen Wess, S. Barak Caine

Journal:

Psychopharmacology

Year:

2007

Language:

english

File:

PDF, 333 KB

english, 2007

24

Increased amphetamine-induced locomotor activity, sensitization, and accumbal dopamine release in M5muscarinic receptor knockout mice

Lene S. Schmidt, Anthony D. Miller, Deranda B. Lester, Cecilie Bay-Richter, Christina Schülein, Henriette Frikke-Schmidt, Jürgen Wess, Charles D. Blaha, David P. D. Woldbye, Anders Fink-Jensen, Gitta

Journal:

Psychopharmacology

Year:

2010

Language:

english

File:

PDF, 483 KB

english, 2010

25

Modulation of prepulse inhibition through both M1and M4muscarinic receptors in mice

Morgane Thomsen, Jürgen Wess, Brian S. Fulton, Anders Fink-Jensen, S. Barak Caine

Journal:

Psychopharmacology

Year:

2010

Language:

english

File:

PDF, 327 KB

english, 2010

26

Increased cocaine self-administration in M4muscarinic acetylcholine receptor knockout mice

Lene S. Schmidt, Morgane Thomsen, Pia Weikop, Ditte Dencker, Jürgen Wess, David P. D. Woldbye, Gitta Wortwein, Anders Fink-Jensen

Journal:

Psychopharmacology

Year:

2011

Language:

english

File:

PDF, 736 KB

english, 2011

27

Signaling of the human P2Y1receptor measured by a yeast growth assay with comparisons to assays of phospholipase C and calcium mobilization in 1321N1 human astrocytoma cells

Ronald T. Niebauer, Zhan-Guo Gao, Bo Li, Jürgen Wess, Kenneth A. Jacobson

Journal:

Purinergic Signalling

Year:

2005

Language:

english

File:

PDF, 262 KB

english, 2005

28

Lithium treatment attenuates muscarinic M1 receptor dysfunction

Thomas K Creson, Daniel R Austin, Galit Shaltiel, Joseph McCammon, Jürgen Wess, Husseini K Manji, Guang Chen

Journal:

Bipolar Disorders

Year:

2011

Language:

english

File:

PDF, 489 KB

english, 2011

29

Recurrence of in-stent restenosis in cardiac allograft vasculopathy following implantation of a sirolimus-eluting stent

Rainer Wessely, Jürgen Pache, Albert Schömig

Journal:

Transplant International

Year:

2005

Language:

english

File:

PDF, 76 KB

english, 2005

30

Multiple muscarinic pathways mediate the suppression of voltage-gated Ca2+ channels in mouse intestinal smooth muscle cells

Yasuyuki Tanahashi, Toshihiro Unno, Hayato Matsuyama, Toshiaki Ishii, Masahisa Yamada, Jürgen Wess, Seiichi Komori

Journal:

British Journal of Pharmacology

Year:

2009

Language:

english

File:

PDF, 1.11 MB

english, 2009

31

An allosteric potentiator of M4 mAChR modulates hippocampal synaptic transmission

Shirey, Jana K, Xiang, Zixiu, Orton, Darren, Brady, Ashley E, Johnson, Kari A, Williams, Richard, Ayala, Jennifer E, Rodriguez, Alice L, Wess, Jürgen, Weaver, David

Journal:

Nature Chemical Biology

Year:

2007

Language:

english

File:

PDF, 1.73 MB

english, 2007

32

Structural basis of G protein–coupled receptor–G protein interactions

Hu, Jianxin, Wang, Yan, Zhang, Xiaohong, Lloyd, John R, Li, Jian Hua, Karpiak, Joel, Costanzi, Stefano, Wess, Jürgen

Journal:

Nature Chemical Biology

Year:

2010

Language:

english

File:

PDF, 1.15 MB

english, 2010

33

Rapid identification of functionally critical amino acids in a G protein–coupled receptor

Li, Bo, Scarselli, Marco, Knudsen, Christopher D, Kim, Soo-Kyung, Jacobson, Kenneth A, McMillin, Sara M, Wess, Jürgen

Journal:

Year:

2007

Language:

english

File:

PDF, 407 KB

english, 2007

34

Heterogeneity of presynaptic muscarinic receptors mediating inhibition of sympathetic transmitter release: a study with M2- and M4-receptor-deficient mice

Anne-Ulrike Trendelenburg, Jesus Gomeza, Werner Klebroff, Hongxia Zhou, Jürgen Wess

Journal:

British Journal of Pharmacology

Year:

2003

Language:

english

File:

PDF, 277 KB

english, 2003

35

M2 and M3 muscarinic receptor-mediated contractions in longitudinal smooth muscle of the ileum studied with receptor knockout mice

Toshihiro Unno, Hayato Matsuyama, Takashi Sakamoto, Mai Uchiyama, Yusuke Izumi, Hiroyuki Okamoto, Masahisa Yamada, Jürgen Wess, Seiichi Komori

Journal:

British Journal of Pharmacology

Year:

2005

Language:

english

File:

PDF, 222 KB

english, 2005

36

Distinct mixtures of muscarinic receptor subtypes mediate inhibition of noradrenaline release in different mouse peripheral tissues, as studied with receptor knockout mice

Anne-Ulrike Trendelenburg, Angelika Meyer, Jürgen Wess, Klaus Starke

Journal:

British Journal of Pharmacology

Year:

2005

Language:

english

File:

PDF, 165 KB

english, 2005

37

Acetylcholine modulates cortical synaptic transmission via different muscarinic receptors, as studied with receptor knockout mice

Nicola Kuczewski, Eugenio Aztiria, Dinesh Gautam, Jürgen Wess, Luciano Domenici

Journal:

The Journal of Physiology

Year:

2005

Language:

english

File:

PDF, 301 KB

english, 2005

38

Muscarinic acetylcholine receptor knockout mice show distinct synaptic plasticity impairments in the visual cortex

Nicola Origlia, Nicola Kuczewski, Eugenio Aztiria, Dinesh Gautam, Jürgen Wess, Luciano Domenici

Journal:

The Journal of Physiology

Year:

2006

Language:

english

File:

PDF, 578 KB

english, 2006

39

Three distinct muscarinic signalling pathways for cationic channel activation in mouse gut smooth muscle cells

Takashi Sakamoto, Toshihiro Unno, Takio Kitazawa, Tetsuro Taneike, Masahisa Yamada, Jürgen Wess, Masakazu Nishimura, Seiichi Komori

Journal:

The Journal of Physiology

Year:

2007

Language:

english

File:

PDF, 1.02 MB

english, 2007

40

Use of M1–M5Muscarinic Receptor Knockout Mice as Novel Tools to Delineate the Physiological Roles of the Muscarinic Cholinergic System

Frank P. Bymaster, David L. McKinzie, Christian C. Felder, Jürgen Wess

Journal:

Neurochemical Research

Year:

2003

Language:

english

File:

PDF, 38 KB

english, 2003

41

Role of acetylcholine and muscarinic receptors in serotonin-induced bronchoconstriction in the mouse

Wolfgang Kummer, Silke Wiegand, Sibel Akinci, Alfred H. Schinkel, Jürgen Wess, Hermann Koepsell, Rainer Viktor Haberberger, Katrin Susanne Lips

Journal:

Journal of Molecular Neuroscience

Year:

2006

Language:

english

File:

PDF, 65 KB

english, 2006

42

M1–M3muscarinic acetylcholine receptor-deficient mice

Dinesh Gautam, Alokesh Duttaroy, Yinghong Cui, Sung-Jun Han, Chuxia Deng, Thomas Seeger, Christian Alzheimer, Jürgen Wess

Journal:

Journal of Molecular Neuroscience

Year:

2006

Language:

english

File:

PDF, 146 KB

english, 2006

43

Methoctramine selectively blocks cardiac muscarinic M2receptors in vivo

Jürgen Wess, Piero Angel, Carlo Melchiorre, Ulrich Moser, Ernst Mutschler, Günter Lambrecht

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

1988

Language:

english

File:

PDF, 457 KB

english, 1988

44

Contribution of both M1and M4receptors to muscarinic agonist-mediated attenuation of the cocaine discriminative stimulus in mice

Morgane Thomsen, Craig W. Lindsley, P. Jeffrey Conn, Jeffrey E. Wessell, Brian S. Fulton, Jürgen Wess, S. Barak Caine

Journal:

Psychopharmacology

Year:

2012

Language:

english

File:

PDF, 446 KB

english, 2012

45

Activation of distinct P2Y receptor subtypes stimulates insulin secretion in MIN6 mouse pancreatic β cells

Ramachandran Balasubramanian, Inigo Ruiz de Azua, Jürgen Wess, Kenneth A. Jacobson

Journal:

Biochemical Pharmacology

Year:

2010

Language:

english

File:

PDF, 402 KB

english, 2010

46

Vasodilatory effects of cholinergic agonists are greatly diminished in aorta from M3R−/− mice

Sandeep Khurana, Ingrid Chacon, Guofeng Xie, Masahisa Yamada, Jurgen Wess, Jean-Pierre Raufman, Richard H. Kennedy

Journal:

European Journal of Pharmacology

Year:

2004

Language:

english

File:

PDF, 292 KB

english, 2004

47

Deoxycholyltaurine-induced vasodilation of rodent aorta is nitric oxide- and muscarinic M3 receptor-dependent

Sandeep Khurana, Masahisa Yamada, Jürgen Wess, Richard H. Kennedy, Jean-Pierre Raufman

Journal:

European Journal of Pharmacology

Year:

2005

Language:

english

File:

PDF, 151 KB

english, 2005

48

Functional roles of muscarinic M2 and M3 receptors in mouse stomach motility: Studies with muscarinic receptor knockout mice

Takio Kitazawa, Kano Hashiba, Jinshan Cao, Toshihiro Unno, Sei-ichi Komori, Masahisa Yamada, Jürgen Wess, Tetsuro Taneike

Journal:

European Journal of Pharmacology

Year:

2007

Language:

english

File:

PDF, 653 KB

english, 2007

49

Antipsychotic-induced catalepsy is attenuated in mice lacking the M4 muscarinic acetylcholine receptor

Anders Fink-Jensen, Lene S. Schmidt, Ditte Dencker, Christina Schülein, Jürgen Wess, Gitta Wörtwein, David P.D. Woldbye

Journal:

European Journal of Pharmacology

Year:

2011

Language:

english

File:

PDF, 379 KB

english, 2011

50

Regulation of CD8+ cytolytic T lymphocyte differentiation by a cholinergic pathway

James C. Zimring, Linda M. Kapp, Masahisa Yamada, Jürgen Wess, Judith A. Kapp

Journal:

Journal of Neuroimmunology

Year:

2005

Language:

english

File:

PDF, 385 KB

english, 2005